Abstract: The luxury hospitality industry is increasingly integrating advanced nutritional science to meet evolving guest expectations for health and wellness. This paper examines the transformative trends and innovations shaping the future of nutritional science in luxury hotels. Key trends include personalized nutrition, which leverages guest data to create customized dietary plans; sustainable and local sourcing, aligning with environmental concerns and ethical consumer preferences; and the use of functional foods, which offer health benefits beyond basic nutrition. Innovations driving this transformation encompass advanced cooking techniques such as sous-vide and molecular gastronomy, which enhance flavor and nutrient preservation; smart nutrition technologies, including apps and wearable devices that provide real-time dietary feedback; and on-site nutritional consultation services, offering personalized dietary advice. Luxury hotels are introducing innovative beverage options, such as infused waters and functional teas, to complement health-conscious dining. By embracing these trends and innovations, luxury hotels are redefining the dining experience, blending opulence with health and sustainability, and setting new standards in the hospitality industry. This paper provides a comprehensive overview of how these elements are reshaping luxury hotel dining and enhancing guest satisfaction through personalized and health-focused offerings.