This study includes facial fractures involving two or three areas of the face, referred to as panfacial fractures (PFFs). Managing PFFs is challenging due to the lack of stable structures for bone continuity. Repairing PFFs requires a systematic approach, but determining the sequence can be difficult. Craniofacial surgeons typically start with the frontal bone and move to the midface in a "top-bottom" sequence. However, oral maxillofacial surgeons argue that this sequence may lead to malocclusion in cases involving both the maxilla and mandible. They propose a "bottom-top" sequence, focusing on the mandible's strength and its relation to the cranial vault. There is debate among surgeons regarding the preferred sequence, with some favoring "bottom-top" and others sticking to "top-bottom." Additionally, there are discussions about "inside-out" versus "outside-in" methods. However, applying a unidirectional sequence is challenging due to the variety and severity of fractures in each patient. Plastic reconstructive surgery (PRS) and oral maxillofacial surgery (OMS) specialists typically perform PFF surgeries, with sequence selection varying between them. This study reviews the literature to compare how sequence selection differs between these specialists and examines fixation sequences in clinical cases of PFFs.