The study titled "Effect of Fertility Levels and Seed Rate on Growth, Yield, and Quality of Wheat (Triticum aestivum L.)" was conducted during the rabi (winter) season of 2020-21 at the student instructional field, Department of Agronomy, Faculty of Agriculture, AKS University, Satna (M.P.), on sandy loam soil. The experiment comprised four fertility levels (0 kg/ha, 50 kg/ha, 75 kg/ha, & 100kg/ha) and three seed rates (S1=80kg/h, S2=90kg/h, and S3=100kg), laid out in a Randomized Block Design with factorial concept and three replications.The findings indicated that nitrogen at 100 kg/ha resulted in superior growth parameters, yield attributing characters, yield, and grain quality compared to other nitrogen levels. Among the seed rates, 90kg/h demonstrated higher growth parameters, yield attributes, yield, and quality characteristics significantly.The treatment combination with nitrogen at 100 kg/ha and seed rate at 90kg/h exhibited significantly higher grain yield, straw yield per hectare, gross and net monetary returns, and benefit-cost ratio (B: C ratio) of wheat. These values, recorded at 5.47 t/ha, 6.83 t/ha, ₹ 104242.65 Rs/ha, ₹ 80392.68 Rs/ha, and 4.51 respectively, were notably superior to other treatments. Regardless of nitrogen fertility levels, seed rate had a pronounced effect on vegetative growth and yield attributing characters in wheat.