This article discussed the diagnosis and treatment of Alzheimer’s disease. In recent years, significant advancements have been developed in the diagnosis and treatment of Alzheimer’s disease. Recent studies and research developed in the genetic field which is helpful in the treatment and diagnosis of Alzheimer’s disease. The newly revised criteria for the diagnosis of Alzheimer's disease are biomarkers for supportive evidence for the pathology. The identification of new susceptibility genes has opened new avenues for exploration of the underlying disease mechanism. In addition to detecting novel risk factors in large samples, next-generation sequencing approaches can deliver novel insights with even small numbers of patients. This common and devastating cerebral degeneration occurs throughout the world and accounts for one-half to two-thirds of all cases of late-life intellectual failure in many developed countries that have achieved high-life expectations. Because the etiology of Alzheimer’s disease remains unclear, fasting hyperinsulinemia has been incriminated in several human diseases, we examined the relationship between Alzheimer’s disease, fasting plasma insulin, glucose, body mass index and waist.