A pre experimental study was conducted to evaluate the effectiveness of self instructional module on knowledge regarding intellectual disability among caretakers of intellectual disability children of Amrita special school Kanpur. The research design was one group pretest post test design. The sample of the study is caretakers of intellectual disability children in Amrita special school Kanpur. The sample size was 40 selected by convenient sampling technique. Consent was taken from the sample before data collection. Demographic data were collected by Structured closed ended questionnaire to assess the knowledge of caretakers regarding intellectual disability.The mean of overall pre test knowledge score was 14.85 and the mean of overall post test knowledge score was 19.775.Improvement in the knowledge score of the samples from pre test to post was tested for statistical significance using paired t-test (t=8.834),shows significance difference between pre and post test score (p0.05)