The battle against the “COVID-19 pandemic” has remained hard for the whole world and in the following study, the context of Pune has been emphasised. This study has evaluated the impacts of the pandemic on Pune, associated risk factors and the battle in response to the pandemic. Several risk factors associated with the virus have been identified, such as gastrointestinal distress, respiratory disorder, headaches, pneumonia, bilateral ground-glass opacities, dyspnoea and cough. Maharashtra remained at the peak of Corona virus infections and Pune became the most vulnerable spot with daily raising infections. The primary quantitative data collection approach has been used in the study and the outcomes have been analysed using the IBM SPSS software. A survey questionnaire containing 10 close-ended questions has been designed and 101 participants have been selected for collecting data. The findings of this study reveal that the pandemic has posed a major disruptive impact on Pune and affected every aspect, including health, business, health services and infrastructure and the economy. Several effective recommendations have been proposed, including upgrading the primary healthcare infrastructure and increasing awareness of the pandemic.