IJFANS International Journal of Food and Nutritional Sciences

ISSN PRINT 2319 1775 Online 2320-7876

Development of functional food formulation; Cardiacare-DM by using Response Surface Methodology

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Puneetha P, Devaki C S, Asna Urooj

Abstract

India's T2DM population is increasing rapidly, with cardiovascular disease complications being the leading cause of morbidity and mortality, which can be prevented by incorporating bioactive compounds into diets. The study aims to enhance Nutricare-DM, a functional food formulation, by adding nigella sativa and zingiber officinale extracts (NSE and ZOE) to "Cardiacare-DM" to reduce CVD risk, using Response Surface Methodology with reference to sensory analysis and glucose adsorption capacity. Among the 13 combinations, taste score ranged from 14.96 to 15.71, flavor 14.91 to 15.74, foldability 16.69 to 17.4, texture 16.68 to 17.46, breakability 16.81 to 17.67, overall acceptability 16.53 to 17.09; GAC in 5mmol @ 1% -0.51 to -0.14 mmol/dL, @ 2% 0.02 to 0.35 mmol/dL, in 10mmol @ 1% 0.9 to 1.96 mmol/dL, @ 2% 0.8 to 2.4 mmol/dL, in 25mmol @ 1% -0.31 to 0.86 mmol/dL, @ 2% 0.4 to 2.33 mmol/dL, and in 50mmol @ 1% 5.65 to 8.57 mmol/dL, @ 2% 8.17 to 12.86 mmol/dL. The study found that 500mg of NSE and 900mg of ZOE were the optimal solutions, with a best-fit desirability of 0.854 and a good overall acceptability score of 17.08, effectively adsorbing glucose at various concentrations.

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