The COVID-19 pandemic and the great lockdown that followed was significant event owing to the long-term effects it had on society, the economy, and development indices. A large number of COVID cases severely strained the systems' limited resources and had an adverse impact on the health systems of the world's nations. COVID-19 was an evaluation of the effectiveness of the healthcare system in a developing nation like India. Even before the pandemic, India, a country with a population of 1.34 billion, had a sizable gap between the quality of cancer care provided in rural and urban areas. The arrival of the pandemic has widened this gap, which will always affect how cancer care is delivered. Thus, along with a discussion of the effects of the COVID-19 pandemic on cancer care delivery in India, the narrative review describes the cancer care infrastructure in India. The article also makes recommendations to prevent the passivity of the cancer care delivery system in the face of emergencies, such as a potential pandemic in the future. The results of the review showed that the reduction in the number of patients reflects the fear of infection combined with the restriction on movement imposed by the great lockdown. Screenings for potential cancers, among other things, were discontinued because this might have increased the risk of viral infections in the asymptomatic and normal populations. Approaches such as telemedicine and virtual consultation are coming up in the management of patients, and specific studies are booming, which paves the way for new ways to practice oncology and conduct clinical trials