Volume 13 | Issue 4
Volume 13 | Issue 4
Volume 13 | Issue 4
Volume 13 | Issue 4
Volume 13 | Issue 4
Cancer is a group of diseases characterized by abnormal cell growth with the potential to invade or spread to other parts of the body. Women with genetic mutations in either BRCA1 or BRCA2 have an increased risk of developing breast and ovarian cancer. The lifetime risk of breast cancer for women with these mutations is estimated to be 82%, while the lifetime risk for ovarian cancer is 54%. Herbal medicine often exerts broad complementary or synergistic effects on physiological systems. Although scientific evidence for the effectiveness of herbal medicine is limited, many people find these remedies helpful, and their use is typically based on traditional practices rather than rigorous research. Centella asiatica is a medicinal herb widely used in folk medicine to treat various ailments. Its main constituents, asiatic acid and asiaticoside, have demonstrated anticancer activity against breast and ovarian cancers. Studies indicate that the growth suppression of cancer cells occurs in a concentration-dependent manner, with cytotoxic effects on SKOV-3 and OVCAR-3 ovarian cancer cells. Centella asiatica also inhibits cell proliferation in MCF-7 breast cancer cells. According to research, there have been no reports of negative interactions between Centella asiatica and medications, highlighting its potential as an anticancer agent.