Antioxidants are an essential component that protects health. Research evidences suggest that antioxidants may lower the risk of chronic illnesses of human being. Present investigation was carried out to appraise the photochemical constituents and antioxidant activity of Dolichandrone falcata seem bark. The bark sample was subjected to Soxhlet extraction with solvents like methanol, chloroform, and pet ether. The antioxidant potential was tested using 2, 2-Diphenyl-1- picrylhydrazyl (DPPH) radical scavenging method. Ascorbic acid was used as a standard control. All the three extracts exhibited antioxidant activity with DPPH inhibition in a dose dependent manner. IC50 values methanol, chloroform, and pet ether extract of Dolichandrone falcata seem bark being 429 µg/ml, 545µg/ml, and 905 µg/ml respectively. Methanol extract showed significant DPPH radical scavenging activity followed by chloroform and pet ether.