The purpose of this research is to evaluate the effectiveness of Terlipressin in conjunction with albumin against albumin alone in treating hepatorenal syndrome in individuals of varying ages and sexes. Twenty-four older patients and sixty-four younger ones were split evenly between the two groups. Everybody got the same amount of respect. Albumin was used alone in Group 1, while albumin and Terlipressin were used in Group 2. IBM SPSS version 20 was used for all statistical analyses in this study. We used frequency analysis and cross-tabulation to create the tables. In this table, we present the means, standard deviations, and medians in that order (minimum–maximum). “Student's t and Mann-Whitney U tests were used to compare continuous variables. Pearson Chi-square and Fisher's exact tests for significance at p 0.05 are necessary for analysis of categorical data. In terms of mean age and distribution of ages, there was no statistically significant difference between the two groups (p = 0.71). This demonstrates that the effect of the current investigation was not modified by the ages of the patients. Researchers also did not find any statistically significant differences in sex distribution between the two treatment groups (p = 0.44). According to the results of this study, both methods of therapy were equally effective for male and female patients. Group 2, which included Terlipressin in addition to albumin, showed a stronger response to treatment than the albumin group alone, despite their being no statistically significant differences between the groups”. Overall, the safety profile was improved when Terlipressin was coupled with albumin.