A REVIEW OF BACILLUS SPECIES ALKALINE PROTEASE PRODUCTION AND INDUSTRIAL APPLICATIONS

Abstract

Protein peptide linkages can be hydrolyzed by protease enzymes. They are present in every living thing and essential to many biological processes and the life cycle of many diseases, bacterial proteases are important medicinal ingredients. Enzyme delivery methods and new technology for rationally engineering proteases will considerably enhance the potential therapeutic applications of enzymes. Proteases are widely used agents in several pharmaceutical business industries. Proteases are present in every living thing. Because of their role in the life cycle of different pathogenic organisms, they could be targeted for the development of therapeutic drugs to treat serious illnesses such as AIDS, cancer, malaria, and bacterial infections. The uses of microbial proteases, including L-asparaginase, L-glutaminase, serrapeptase, serrazime, and L-asparaginase, are the primary emphasis of this review. These enzymes are being utilized to treat cancer, respiratory illnesses, cardiovascular disease, and inflammation.