Optimization of a Robust HPLC Method for Abemaciclib and Its ProcessRelated Impurities; Characterization of Degradation Products Using LCMS/MS

Authors

  • Srinivasa Rao Katta1* Author
  • Gajanand Thakre2 Author

Abstract

The current study was undertaken to explore an innovative approach that employs liquid chromatography (LC) and liquid chromatography-mass spectrometry (LCMS/MS) for the resolution, identification, and characterization of minute quantities of degradation products (DPs) of abemaciclib, without the need for their isolation from reaction mixtures.

Published

2022-01-01

Issue

Vol. 11 No. 3 (2022)

Section

Articles

How to Cite

Optimization of a Robust HPLC Method for Abemaciclib and Its ProcessRelated Impurities; Characterization of Degradation Products Using LCMS/MS. (2022). International Journal of Food and Nutritional Sciences, 11(3), 973-991. https://ijfans.org/index.php/Journal/article/view/5328