Restoration of Ovulatory Function and Endometrial Receptivity through Ayurvedic Intervention in a Case of Infertility with PCOD and Hypothyroidism

Abstract

Introduction: Infertility, a global health concern affecting 10–15% of couples, is commonly linked with anovulatory disorders such as polycystic ovarian disease (PCOD) and endocrine imbalances like hypothyroidism. Modern therapeutic approaches—including ovulation induction and assisted reproductive technologies (ART)—often offer limited or temporary success, leading to growing interest in holistic alternatives. Ayurveda describes infertility as Vandhyatva, primarily resulting from Agnimandya, Srotorodha, and Artavavaha Srotas Dushti, which disrupt Rutu, Kshetra, and Artava-utpatti. Methods: A 33-year-old woman with a 10-year history of primary infertility, PCOD, hypothyroidism, and thin endometrium (0.92 mm) presented with dysfunctional uterine bleeding and failed IVF attempts. Ayurvedic management was planned based on Samprapti Vighatana and classical protocols involving Deepana–Pachana, Virechana Karma, and Uttarabasti, supplemented with Rasayana and Artavajanana formulations—Vasantakusumakar Rasa, Tapyadi Lauha, Phalaghrita, and Putrajivaka–Shivlingi Bija Churna. Virechana was performed using Trivrit Avaleha, followed by Uttarabasti with Phalaghrita for six consecutive days. Results: Sequential ultrasonography showed follicular growth from 13.3 mm to 20.2 mm, and endometrial thickness improved from 0.92 mm to 8.4 mm. Ovulation was confirmed on the 14th day. Clinically, the patient reported normalized menstrual rhythm, improved energy, appetite, and reduced fatigue. Discussion: Therapeutic interventions corrected Agnimandya and Srotorodha, rejuvenating Artavavaha Srotas and restoring the physiological state of Rutu, Kshetra, and Artava-utpatti. The synergistic action of Phalaghrita and Putrajivaka–Shivlingi enhanced folliculogenesis and endometrial receptivity, while Virechana and Deepana–Pachana facilitated systemic detoxification and hormonal equilibrium. Conclusion: This case demonstrates the efficacy of an integrative Ayurvedic regimen in managing infertility associated with PCOD and hypothyroidism by restoring reproductive balance and promoting ovulation. Further controlled studies are warranted to substantiate these findings.