An ethno medicinal study based on investigation, documentation and exploration have been done on the status of medicinal plants and associated knowledge of ethnic people of Bermo-subdivision of Bokaro district of Jharkhand. The study based on questionnaire, semi-structured interviews, field observations and study of flora. Lastly the data was collected and evaluated. A total of 45 medicinal plant species used to treat 64 different common and critical illnesses were recorded. A total of 104 knowledgeable members of tribal community were interviewed for obtaining the knowledge of use of 45 medicinal plants. Most experienced and aged person of the community got plenty of knowledge of traditional use of plants. Leaves are most commonly used plant parts for tribal medication. Biological resource that is plants and associated organisms are reducing day by day due to pollution, deforestation, population explosion, agriculture, wood extraction, construction and overgrazing as informed by the villagers and experts. The floristic investigation aims to scientifically record the data for human welfare and ensuring conservation by creating awareness towards sustainable utilization and management of these medicinal plant diversity.