Background: Given that essential hypertension is generally asymptomatic and undiagnosed, it has been appropriately termed the silent killer. Every organ can be damaged by uncontrolled hypertension. Hyperlipidemia and hypertension are the most prominent risk factors for coronary artery disease (CAD). Those with a combination of risk factors are particularly prone to coronary artery disease. Aims & Objective: Compared the aberrant lipid profile (TC, TG, HDL, LDL, VLDL) of hypertension patients to that of healthy individuals. Methods & Materials: The proposed research would be done at the Department of Medicine, Santosh Medical College, Santosh University, Ghaziabad, on patients attending the Santosh Hospital Medicine OPD/IPD. From January 2014 to January 2015, the duration of the study will be one year. The following is a case-control study. There were 100 male and female participants between the ages of 31 and 60 who were of the same age and gender. Results: This survey reveals that 38% of individuals are in their fifth decade of life, 19% are male and 19% are female, 23% are in their fourth decade, 15% are male and 8% are female, and 14% are in their third decade, 9% are male and 5% are female. Conclusion: Serum lipid profile can serve as an important marker for cardiovascular disease screening in hypertensive persons, and early diagnosis of cardiovascular disease can reduce cardiovascular morbidity and mortality. In addition, total cholesterol, HDL-C, LDL-C, and BMI were found to be abnormal in hypertensive people in my study, although triglycerides and VLDL-C did not substantially differ with hypertension.