The resistance to corrosion and temperature, along with the high strength-to-weight ratio of titanium alloys, makes them extensively utilized in turbine engines and aircraft structures. To achieve the desired shapes with precision, machining of these alloys necessitates advanced techniques such as abrasive water jet machining (AWJM). In this paper, a collection of optimal AWJM parameters, including traverse speed, abrasive flow rate, and stand-off distance, is presented. These parameters are aimed at maximizing the material removal rate (MRR) while minimizing the surface roughness (Ra) of the Ti-6Al-4V alloy. Utilizing a multi-objective optimization technique, the study applies Taguchi's L9 orthogonal array to analyze multiple response test data. Furthermore, an analysis of variance (ANOVA) is performed to assess the statistical significance of the AWJM parameters.