Background: Considering that it is typically asymptomatic and undiscovered, essential hypertension has been properly dubbed the silent killer. Uncontrolled hypertension can harm every organ in the body. Dyslipidemia and hypertension are the most prevalent coronary artery disease risk factors (CAD). Those with a mix of risk factors are especially susceptible to coronary artery disease. Aims & objectives: To compare the abnormal lipid profile (TC, TG, HDL, LDL, VLDL) of hypertension patients with healthy individuals. Methods & Materials: The proposed research would be conducted at the Department of Medicine, Santosh Medical College, Santosh University, Ghaziabad, on patients attending the Santosh Hospital Medicine OPD/IPD. From January 2014 to January 2015, the study will be done over the course of one year. This is a case-control analysis. There were 100 age- and gender-matched male and female participants between 31 and 60 years old. Results: This study shows that 38% of instances are in their fifth decade of life, with 19% male and 19% female, 23% are in their fourth decade, with 15% male and 8% female, and 14% are in their third decade, with 9% male and 5% female. Conclusion: It was determined that serum lipid profile can serve as an important marker for cardiovascular disease screening in hypertensive individuals, and that early detection of cardiovascular illness can reduce cardiovascular morbidity and mortality. In addition, in my study, total cholesterol, HDL-C, LDL-C, and BMI were found to be abnormal in hypertensive individuals, although triglycerides and VLDL-C did not differ significantly with hypertension.