By using elemental analysis, molar conductance, IR, NMR, and electronic spectrum data, a number of organic compounds and their Zn(II), Cd(II), and Hg(II) metal complexes have been created and described. Using the agar-well diffusion method, these compounds were tested for antibacterial activity against the bacteria Basillus Subtillus, Staphylococcus aurus, Escherichia coli, and Salmonella typhi. All of the synthetic compounds have demonstrated good antibacterial and/or antifungal activity, which was typically enhanced upon complexation with metal ions