Background: Systolic pressure greater than 140 mmHg and diastolic pressure greater than 90 mmHg describe hypertension in adults (1). Due to the high blood volume, hypertension caused by (secondary to) established disease processes, such as kidney disease and arteriosclerosis of the renal arteries, is properly referred to as secondary hypertension (2). Hypertension caused by complicated and poorly understood processes cannot reasonably be referred to as primary or essential. Aims & Objectives: To study the correlation of Renal dysfunction with clinical profile and complications of essential hypertension Methods & Materials: Patients with a diagnosis of Hypertension who visited the Medicine Department of Santosh Medical College and Hospital in Ghaziabad between May 2014 and April 2015 were evaluated based on inclusion and exclusion criteria (May 2014 to April 2015). A Case-Control study on renal failure in essential hypertension was undertaken at Santosh Medical College and Hospital in Ghaziabad, Uttar Pradesh, using 100 patients as cases and 25 patients as controls. Results: 36 patients (36.0%) had hypertension less than or equal to 1 year, 44 patients (44.0%) had hypertension between 1-5 years, 3 patients (3.0%) had hypertension between 6-1 years, and 17 patients (17.0%) had hypertension between 11-22 years. Conclusion: The frequency of renal impairment varies between groups based on demographic factors and evaluation instruments and processes. Hypercholesterolemia, hypertriglyceridemia, and elevated LDL are all characteristics of essential hypertension. The prevalence of hyperuricemia increases with patient age, hypertension duration, and severity. In order to promote better categorization of absolute cardiovascular and renal risk factors, hypertensive subjects should have a more thorough evaluation of their renal function, especially in patients with hypertension that has been present for more than five years