The growth of nanoscale molecular probes accomplished of identification, characterization, and medical treatment of disease leads tocreation of imaging technologies. Such probes are significant to inflammationmainly, where the recognition of early disease could simplifytreatment strategy and enhanced, custom-made therapies. This proposes that nanotechnology may offeroutstanding biomarkers for the diagnosis of inflammatory diseases through various techniques like magnetic resonance imaging (MRI), fluorescent quantum dots (QDs), and Raman scattering probes. In this article we will discuss various aspects of NPs in the treatment and diagnosis of inflammation and their applicability in inflammatory diseases.