For the measurement of Clozapine drug in pure form and pharmaceutical formulations, a quick, sensitive, and easy spectrophotometric approach was devised and validated. The suggested procedure is based on the creation of a binary complex between these drugs and eosin Y in an aqueous acetate buffered media. The binary complex was formed under the optimum conditions which shows absorption maxima at 545 nm. Beer’s law is obeyed in the concentration range of 1.0 - 10 μg/ml . Molar absorptivity and Sandell’s sensitivity are found to be 1.1176 x 104 L mol-1cm-1 and 0.0291 µg/cm2 respectively. The limit of detection (LOD) was 1.1152 µg/mL & the limit of quantitation (LOQ) was 3.3796 µg/mL for the Clozapine drug. It was observed that the excipients that are commonly present in pharmaceutical formulations did not interfere. The proposed method was successfully applied to the analysis of Clozapine tablets in their dosage forms.