Radicular cysts or periapical cysts are the most common types of inflammatory cysts to affect the jaw bones. Radicular cysts may account for up to as many as 70% of all cystic jaw bones lesions. These cysts are through to be the end results of epithelial cell rests proliferating during inflammation of teeth with infected and necrotic pulp, and apical periodontitis. Unless the cyst becomes infected, they are usually asymptomatic. Typically, they present as osteolytic periapical lesions detected with radiographic imaging. Radicular cysts, when seen on radiographic imaging, tend to appear pear shaped or round. Lesions are typically less than 1 cm in size and are situated in the periapical region of teeth with unilocular and lucent characteristics. During the past few decades several authors haveperpetuated the notion that nearly half of all periapical lesions are radicular cysts. A few studies, based on meticulous serial sectioning of periapical lesionsretrieved have shown that the actual incidenceof radicular cyst is only about 15% of all periapical lesions. Equally significant was the discovery in 1980 and recent confirmation that radicular cysts exist in two structurally distinct classes namely, those containing cavities completely enclosed in epithelial lining (periapical true cysts) and those containing epithelium-lined cavities that are open to the root canals (periapical pocket cysts). From a clinical point of view a periapical pocket cyst may heal after conventional root canaltherapy whereas an apical true cyst is less likely to be resolved without surgical intervention.