IJFANS International Journal of Food and Nutritional Sciences

ISSN PRINT 2319 1775 Online 2320-7876

PHYTOSOMES IN DRUG DELIVERY SYSTEM

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Shubhrat Maheshwari, Jagat Pal Yadav, Ajeet Kumar, Alka, Ravi Kumar, Abhishek Mishra, Shailendra Singh Bhadauriya, Somesh Shukla, Neelam Jain

Abstract

The science of medication delivery has recently paid a lot of attention to phytosomes, which are a specialized delivery method. Unique structures with improved bioavailability and therapeutic efficiency are produced when active chemicals obtained from plants are complexed with phospholipids. This presentation offers a synopsis of phytosomes' potential as drug delivery vehicles. Improved solubility, stability, and absorption of poorly soluble phytoconstituents are only a few of the many benefits of using phytosomes in medication administration. Phytosomes are absorbed more easily into the body and their active chemicals are more readily absorbed because their phospholipid bilayer structure resembles the cell membrane. Furthermore, stability and shelf life are improved because to the interaction between phytoconstituents and phospholipids, which offers protection against degradation. Phytosomes have showed considerable promise in both preclinical and clinical investigations as medication delivery vehicles. When compared to standard formulations, they show considerable improvements in pharmacokinetic profiles, tissue targeting, and therapeutic effectiveness. Additionally, phytosomes have an impressive safety record, with few reports of negative side effects. This abstract emphasizes phytosomes' potential as a fresh strategy in medication delivery. More study is needed to determine their potential clinical use, determine the best formulation characteristics, and evaluate their long-term safety. Researchers and pharmaceutical scientists may improve the distribution of phytoconstituents and broaden the scope of customized treatment by taking use of the distinctive characteristics of phytosomes.

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