Background- The main purpose of the study was to find out the influence of plyometric training on acceleration and agility of men football players. Methodology-In this study, the researcher has selected a total of ten (10) men football players who have participated in at least one intercollegiate tournament and are presently students at ICFAI University, Tripura. The age range of football players was 17 to 23 years, respectively. A six-week plyometric training programme was applied three days a week on an alternative basis. The pre-test and post-test data were collected through the RAST test for acceleration and the SEMO test for agility. Results-After six-weeks of training, the mean acceleration time decreased from pretest.1967 to post-test.1303 and the mean agility time decreased from pretest 13.4300 to post-test 13.0650 in the plyometric training group. The statistical tools were used in a paired t-test with the help of SPSS software version 20. The level of significance was fixed at 0.05. Conclusion-The results of the study concluded that plyometric training is helpful to improve acceleration and agility. It is possible that plyometric training improves the acceleration and agility of men football players.