Increased provision of health care in outpatient settings and worries around occupational transmission of illnesses have heightened awareness of the risk of Infectious illness transmission in ambulatory health care settings. Unlike nosocomial infections in hospitals, diseases transmitted to outpatients Settings are neither routinely monitored nor are they likely to be detected by standard qi surveillance. We analysed the literature to find cases and clusters of infections related with outpatient health care in order to better describe the range of such events. We discovered and epidemiologically described 53 such occurrences from 1961 to 1990 as part of this review. Transmission has occurred in general medical offices, clinics, and emergency departments (13), ophthalmologists' offices and clinics (11), dentistry offices (13), and alternative-care settings (13). (six). Our findings imply that inpatient infection-control strategies should be expanded to outpatient health care settings by assigning particular responsibilities for infection control and adopting surveillance and prevention methods.