Moringa oleifera is a miraculous tree, with multiple edible parts, each having unique nutritional and medicinal properties. In the past, M.oleifera was used in traditional healing practices, and currently, it is incorporated into everyday food products. It serves as a plentiful reservoir of essential vitamins, minerals, and proteins. The abundance of nutraceuticals present in M.oleifera is responsible for its immense bioactive properties that could prevent or alleviate many diseases. Bio-fortification has become an emerging concept to deal with nutritional deficiencies, and the fortification of M.oleifera has been found to be effective in combating malnutrition. Ever since green nanotechnology has evolved, several attempts are being made to synthesize nanoparticles using extracts of M.oleifera and to further characterize their properties. In this comprehensive review, we delve into the phytochemical and bioactive characteristics of M.oleifera, its function as a potent bio-fortificant, and its potential as a green tool in the synthesis of nanoparticles.