Background: Diabetes has long been recognised as a risk factor for both current and reactivated tuberculosis (TB). Diabetes increases the risk of tuberculosis by a factor of three (TB). Consequently, the incidence of tuberculosis is higher among diabetics than in the general population, and diabetes is a common comorbidity in TB patients. There is scientific evidence linking the two disorders, as indicated by systematic reviews. Diabetes and TB may exacerbate one another on multiple ways. Aims & objectives: To examine the glycemic profile of pulmonary TB cases that are active Methods & Materials: Department of Medicine, Santosh Medical College & Hospital, Ghaziabad, Uttar Pradesh, was where the research was conducted. Outpatients and inpatients of the medicine department at Santosh Hospital in Ghaziabad, Uttar Pradesh. Included in the study were a total of 100 consecutive cases of active pulmonary TB and 30 age- and gender-matched healthy controls. Results: Poor glycaemic control and Co-morbid diabetes was seen in 15% cases of TB as compared to 0% controls (p<0.01).Urine sugar was seen in 21% cases of TB as compared to none in control group(p<0.01).No significant association was observed between glycaemic control status andsputum AFB results in spot sample (p-0.544).No significant association was observed between glycaemic control status and sputum AFB results in morning sample (p-0.85). Conclusions: In accordance with the new WHO End TB Strategy, we advise that greater efforts be made to integrate programmes for non-communicable and communicable diseases in order to increase the overall impact of disease control and prevention. In actuality, the exhaustive programme.Management of DM-TB should involve avoidance of DM, early identification of DM, and glycemic control. When both tuberculosis and diabetes are treated concurrently, good glycemic control may enhance health outcomes. If individuals with tuberculosis also have diabetes, therapeutic monitoring may need to be intensified.