The severe consequences of contamination with heavy metals that are occurring all across the globe, are becoming a problem and a cause for alarm. Due to the metallurgical and agricultural sectors' fast expansion. These inorganic pollutants are discharged by industry, poor waste management, fertilizers, and pesticides into our rivers, soil, and ecosystem. The main objective of this research is to inform readers about the risks posed by heavy metals and other dangerous elements. Consequently, the ecosystem of the planet suffers. While certain metals collect in one or more organs and cause a range of serious disorders, including tumors, other metals tend to interfere with normal growth and function. Human toxicological processes for each metal are studied from a pharmacokinetics perspective. This study's overview explains how pollutants move through the environment as well as what transpires to them. The desire for willful destruction of the planet's common property has increased as a result, worsening the pollution situation worldwide. In this study, the degree of disease severity, risk factors, as well as biological and physical characteristics of individuals with significant metallic bio-accumulation would be disclosed.