Recent years have seen a significant shift in drug delivery technologies. Modern efforts are concentrated on minimising risks while maximising benefits. Launching additional compounds is expensive, so instead, the industry is focusing on making the ones it already has more effective. Therefore, new infusion methods such as closed loop infusion, target controlled infusion, and controlled release have emerged. It is possible that applying pharmacokinetic principles, rather than quantitatively determining drug dose, might increase patient safety and help to keep drug levels stable in the body. Applying computers to a welldesigned operating system can only boost its effectiveness. Most of these once-research-only technologies are now routinely used in clinical settings. Because of this, it is essential for today's clinicians to become conversant with these tools. Here, we've focused on the newest drug delivery methods that can be used in anesthesiology.