Background: Preterm delivery is a major cause of perinatal morbidity and mortality in developing countries. Maternal urogenital tract infection is a common cause of preterm labour. Infection with Trichomonus vaginalis, Bacteroids species or Urea plasmaurelyticum has been found to be associated with increased risk of preterm birth, preterm delivery and PROM. Aim and Objective: The present study was aimed to study Genito-urinary infections among pregnant patients diagnosed as threatened preterm labour and its fetal outcome Methodology: At Santosh Medical College and Hospital in Ghaziabad, this case control observational study took place between April 19 and September 30, 2020. There were 120 pregnant women recruited, of whom 60 had threatened preterm delivery and were placed in the case group. The other 60 antenatal women, who had reached 37 weeks but were still under 40 weeks, and who had not experienced any pregnancy complications during the current pregnancy, were placed in the control group. Pregnant women were screened for data by considering their medical histories, physical examination results, and test results. Result: Preterm was in 3.33% of controls and in 41.66% of cases. LBW were 16.66% in controls and 45% in cases. There was statistically significant (p=0.03) difference in adverse fetal outcome between cases and controls. Conclusion: Our study revealed that revealed that there is a significant impact of urogenital infection on preterm labour as well as adverse fetal outcome.