Obesity as a common chronic disorder of excessive body fat and has become a global epidemic. In Ayurveda, an individual whose increased Meda and Mamsa Dhatu makes his hips, abdomen and breasts pendulous and whose vitality is much less than his body size is Sthoola (obese). Acharyas have described it for all Santarpanajanya Vyadhi. Concept of Apatarpana is one of the most important basic treatment principles of Ayurveda. Acharya Sushruta has mentioned, Sthaulya and Karshya depend upon the quality and quantity of Ahararasa. So we can say that Ahararasa plays a major role for increasing Meda Dhatu in Sthaulya. Viharatmaka Nindanas are activities having Abhishyandi properties like Divaswapna & Avyayama. Harshanitya and Achintana are two psychological factors responsible for Sthaulya. Acharya Bhavmishra mentions that increased proportion of Meda and decreased proportion of Shukra in Beeja at the time of conception predisposes towards development of Sthula but weak body of offspring. Samprapti of Sthaulya includes obstruction of Srotas by vitiated Meda, Vata move into Koshtha and increases the Agni, which absorbs the food fastly. The corpulent person digests the food speedily and craves for food inordinately. Over eating produces more Rasa, which results in over production of Meda Dhatu, which leads to Sthaulya. Administration of Dravya having Guru and Aptarpana properties and also possess additional Vata, Shleshma and Medohara properties is considered as an ideal therapy for Sthaulya.