Severe acquired respiratory syndrome coronavirus-2 (SARS-CoV-2), also known as COVID -19, is an extremely transmissible virus that has emerged as a pandemic. Currently, SARS CoV-2 is the most serious health issue which causing unexpected higher rate of death globally. To conflict this condition, people may benefit from the healing properties of medicinal plants, such as strengthening the immune system and creating antiviral effects. This study brings together traditional medicinal plants and their bioactive components to summarize and discuss techniques for combating viral diseases in general and strengthening the immune system in particular. The Crude extract or pure compounds isolated from medicinal plants and herbs have shown promising inhibitory effect against corona virus. Meanwhile, a number of alternative therapies are being explored for effective disease management. Various herbal medicines and essential oils have been reported to have antiviral activity, but this has not been well studied in the context of SARS-CoV-2. Researchers and medical organization are working to identify antiviral drug candidates. This review focused on the biology of the infection and various related therapeutic strategies, including drug repurposing and phytomedicines.