Oral Submucous Fibrosis (OSMF) is a precancerous condition affecting the oral mucosa, oropharynx, and, rarely, the larynx. It is primarily caused by habits such as areca nut chewing, pan masala chewing, smoking, and consuming hot and spicy foods like chilies. Various treatment modalities are employed to provide symptomatic relief. This article compiles published literature on adjuvant therapies for treating OSMF. The literature suggests the use of garlic, curcumin, tulsi, aloe vera, spirulina, and lycopene as treatment options for OSMF. The relevant studies indicate that these adjuvant therapies offer a natural and cost-effective treatment option. Additionally, lifestyle modifications can aid in curing the disease. However, further studies are needed to enhance awareness and encourage the use of these non-invasive therapeutic modalities as primary treatment options by patients.