Spinel Ni-Zn1-xFe2O4 (x = 0.0 and 0.5) nanoparticles were synthesized by simple microwave combustion method. The structural, morphological and magnetic properties of the Ni-Zn ferrites were determined by X-ray diffraction (XRD), high resolution scanning electron microscopy (HR-SEM) and vibrating sample magnetometer. The XRD confirms that all the compositions crystallize with cubic spinel ZnFe2O4. HR-SEM images revealed that the asprepared samples are crystalline with particle size distribution in 22-27 nm range. The saturation magnetization (Ms) increased with increase in Ni content.