The present paper is based on Ayurvedic disease “Madatyaya.” Here we can compare it with modern disease “Alcoholism”. In Charak, Sushruta, Bhavaprakash, Madhavnidan, Chakradatta, Bhaisahajya ratnavali , Vangasen Samhita we also get description of madatyaya. According to Ayurveda alcohol taken in accordance with proper procedure, dose, time, combination of food, etc. and of body strength gives happiness and acts like nectar. Madya taken indiscriminately without taking food and in an improper amount acts like a fire and mixing with body heat causes very severe intoxication and other diseases similar to it. (Vangasena chi. Sang.) There are many references for Ayurvedic management of Madatyaya that we have to apply in modern time. Finally main intention for presenting this paper is to share basic details of Madatyaya for proper Treatment.