IJFANS International Journal of Food and Nutritional Sciences

ISSN PRINT 2319 1775 Online 2320-7876

PHYTOCHEMICAL SCREENING, EVALUATION OF ANTIOXIDANT PROPERTY OF DIFFERENT MEDICINAL PLANTS AND ANTIDIABETIC PROPERTY OF GROUNF APPLE

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Dr. C. Vijitha, Mrs. Syed Husna Fathima, Mr. M. Vijay Reddy

Abstract

Context. There are several medicinal chemicals found in plants that have wide-ranging uses in the pharmaceutical sector. This study sought to determine which phytochemicals were found in the seven chosen medicinal plants, as well as the antibacterial and antioxidant properties of these compounds. Techniques. Phytochemical screening, total phenolic content, and favonoid levels were measured by means of conventional techniques. Using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl (OH), and nitric oxide (NO) radical scavenging tests, the antioxidant activity of plant extracts was assessed. The broth microdilution method was used to assess the plant extracts' antibacterial properties. Conclusions. The phytochemical investigation revealed that all plant extracts contained phenols, favonoids, and steroids. The highest total phenolic and flavonoid concentrations were found in the extract of Psychotria peduncularis, which had 5.57 ± 0.22 mg GAE/g and 1.38 ± 0.06 mg QE/g, respectively. The DPPH and NO radical scavenging activities of all plant extracts demonstrated extremely significant antioxidant activity, with IC50 values ranging from 0.55 to 49.43 µg/mL and 0.65 to 13.7 µg/mL, respectively. The antibacterial activity of P. peduncularis and Tristemma mauritianum extracts was significant, with MIC values ranging from 16 to 1024 µg/mL. All investigated species were resistant to the bactericidal effects of T. mauritianum extract. The antifungal activity of P. peduncularis and Alsophila manianna extracts against the Candida albicans strain was significant (MIC 64 µg/mL). In conclusion. The screened extracts of medicinal plants utilized in our investigation may be employed as resources for the creation of novel medications as well as possible antioxidant and antibacterial agents.

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