Pacchai Karpoora Mathirai is a herbo-mineral siddha formulation for the treatment of kabasuram (Bronchitis). Aim and objective: To estimate the phytochemical analysis of pacchai karpoora mathirai. Materials and Methods: The drug was prepared as mentioned in the classic siddha literature (Bala vagadam). The physico-chemical analysis such as loss-on-drying method or LOD, total ash, insoluble ash, water soluble ash, water soluble extractive and alcohol soluble extractive were carried out. Results: The physico-chemical analysis revealed that the loss on drying was 13.98, total ash was 4.15, acid insoluble ash was 0.7, water soluble ash was 2.60, water soluble extraction was 7.81 and alcohol soluble extraction was 25.33 and pH value was 5.17. The physicochemical analysis of the test drug Pacchai Karpoora Mathirai was carried out as per WHO guidelines (Quality control methods for medicinal plant materials -1998). The test procedures were done at Central Research Institute, Arumbakkam, Chennai.