Nutrigenomics represents a dynamic field at the intersection of genetics, nutrition, and healthcare, focusing on understanding how an individual's genetic makeup influences their response to dietary components. This paper provides an overview of nutrigenomics, elucidating its significance in personalized nutrition and its potential health benefits. We delve into the genetic basis of nutrigenomics, exploring how genetic variations impact nutrient metabolism, absorption, and utilization. The paper discusses the potential health benefits of personalized nutrition plans informed by nutrigenomic insights, including disease prevention, weight management, and optimizing athletic performance. Challenges such as ethical considerations and the interplay between genetic and environmental factors are also addressed. Furthermore, technological advances such as Next-Generation Sequencing (NGS), microarray technology, and artificial intelligence are highlighted for their role in advancing nutrigenomics research and making genetic testing more accessible. Integration into healthcare, including precision medicine initiatives and educational efforts for healthcare professionals and the public, is explored. The abstract concludes with insights into the future directions and implications of nutrigenomics, emphasizing its potential to revolutionize personalized healthcare and improve health outcomes on a global scale.