Drug pharmacokinetic parameters and biopharmaceutical properties play a significant role in drug safety and efficacy because they regulate the standard and quality of the medicine’s ability to achieve intended goal. Long-acting medicine delivery technologies with multiple dosing frequencies encounter very serious problems including sub therapeutic plasma drug concentration, lower bioavailability, side effects and systemic toxicity leading to the poor conformity of patient. Using polymer platform to distribute drugs can resolve these issues. Platform technology can accommodate pharmaceuticals with similar physicochemical/therapeutic qualities while requiring little modification. Nanoparticulate drug delivery system, micro encapsulations, mucoadhesive techniques, self-micro emulsifying drug delivery systems (SMEDDS), nasal DDS, transdermal DDS, floating DDS are some of the potential representative polymer platform technologies that can address the issues related to conventional drug delivery technologies. Various synthetic, semisynthetic and natural polymers are utilised in the polymer platform technology including Chitosan, Ethyl cellulose, Poly (glycolic acid), poly lactic acid, “Hydroxy propyl methyl cellulose”, “Carboxy methyl cellulose” and “Poly vinyl pyrrolidone” etc. This review article describes the need, advantages, various challenges and future perspectives associated with polymer platform DDS.