Oral organization is the most advantageous mode among different prescription conveyance ways since it offers greatest patient implementation. Low water dissolvability and poor enzymatic/metabolic dependability of prescriptions, then again, are critical restrictions in proficient oral medication organization. There are numerous approaches to resolving the issue of hydrophobic medications. Among the many methodologies, the nanotechnology-based drug conveyance technique can possibly resolve the issues related with the oral course of organization. There are new prescription conveyance techniques accessible in different fields of medication. The utilization of these gadgets in the treatment of hypertension is developing. The ongoing review centers around the numerous nano transporters accessible in oral medication conveyance to further develop the dissolvability profile, disintegration, and in this manner bioavailability of hydrophobic antihypertensive prescriptions. When contrasted with different strategies, for example, intramuscular, intravenous, and aspiratory, oral prescription conveyance is the most well known, direct, and broadly used. It gives benefits like effortless organization, no guide, as well as understanding consistence.