PCOS is one of the most commonly reported endocrine and metabolic disorders among women of reproductive age. It is a heterogeneous condition characterized by features of androgen excess and ovarian dysfunction symptoms in the absence of another diagnosis. Although the etiopathology of PCOS is not so well proven, accumulating evidence suggests that it is a multi-gene condition with substantial epigenetic and environmental impacts, including nutrition and lifestyle variables. Menstrual abnormalities and reproductive dysfunction are the most commonly reported signs of PCOS, leading to female infertility. The World Health Organization (WHO) data suggests that approximately 116 million women (3.4%) are affected by PCOS globally. In India, it affects 3.7% to 22.5% (1.3-7.9 crore) of women. Aim: To assess the awareness of women on prevention of PCOS. Material & Methods: The method used is a descriptive, quantitative research approach with a Non-experimental research design was adopted along with a self-structured tool to collect data from 304women from rural and urban parts of Navi Mumbai and Kerala. Results: The total number of participants were 304. Majority 71% of the participants were in the age group of 18 to 26, 69.9% of women belong to urban community, 88.8% of participants were single and 51.5% of participants were undergraduates. The level of awareness of PCOS in this study was 87%. Among the aware females, majority were aware about the causes and prevention of PCOS. Conclusion: The awareness of women on PCOS and its prevention among women was high. With enhancement of knowledge the implementation of modified lifestyles practices is also important.