IJFANS International Journal of Food and Nutritional Sciences

ISSN PRINT 2319 1775 Online 2320-7876

IONIC LIQUID - TETHERED COLLOIDAL SILICA NANOPARTICLES AS A REUSABLE AND EFFECTIVE CATALYST FOR THE SYNTHESIS OF PHENAZINES

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THARAGESWARI. K,Dr. G. PADMAPRIYA

Abstract

Heterocycle synthesis has long been a vital and rapidly expanding field of organic chemistry, since heterocycle molecules exhibit a wide variety of biological functions [1-5]. Antitumor [6, antibacterial [7], anti-proliferative [8, antifungal [9], and anti-inflammatory [10] are some of the biological characteristics of phenazines. Phenazines are noteworthy candidates in organic preparation for future consideration because of these characteristics. For the manufacture of phenazines, a variety of methods have been established utilising p-TSA [11], glacial acetic acid [12], 1,4-diazabicyclo[2.2.2]octane (DABCO) [13,14], thiourea-based organocatalysts [15], caffeine [16], theophylline [17], L-proline [18], 1-butyl-3-methylimidazolium Each of these methods may have its own set of benefits, but they all have obvious disadvantages, such as lengthy reaction durations, difficult set-up, non-reusable catalyst, poor yield, or potentially dangerous reaction conditions. To get over these limitations, finding an efficient, readily available catalyst with high catalytic activity for the production of phenazines is still the best option. The production and immobilisation of nanoparticles in ionic liquids (ILs) have been extensively studied in recent years [21,22]. Ionic liquids may be thought of as important catalytic precursor chemicals [23, 24]. The nature of cation-anion interactions in ionic liquids at room temperature is a topic of growing interest [25,26]. [27,28] examined the structures of 1-ethyl-3- methylimidazolium (Emim) and 1-butyl-3-methylimidazolium (Bmim) with transition metal chloride anions such as NiCl42-, CoCl4 2-, and PdCl42-.

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