A extremely uncommon condition known as calcinosis cutis is characterized by calcium deposits in the skin and subcutaneous tissue. Rarely has idiopathic calcinosis cutis been documented in the literature. In the cases recounted here, two healthy females in their 40s and 55s presented with many asymptomatic hard nodules on the tips of their palms. The diagnosis of idiopathic calcinosis cutis was confirmed by thorough blood investigations, radiographic tests, and histopathological analysis