IJFANS International Journal of Food and Nutritional Sciences

ISSN PRINT 2319 1775 Online 2320-7876

Formulation And Evaluation Of Felodipine Bilayered Tablet

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Rashi Agrawal1, Shehnaz Sheikh1, Kanishka Mathur1, Deepak Joshi2, Kiran Verma1, Deepti Andheriya Modi3, Ishan Dubey1*

Abstract

Hypertension is a major risk for Cardiovascular and stroke complications. The good permeability and the poor water solubility (BCS class II) as well as short biological half-life characteristics of Felodipine selected as a drug candidate for bilayer preparations. Felodipine belongs to dihydropyridine derivative, which acts as a calcium channel blocker, used as an anti-hypertensive drug. Here the aim was to combine two Felodipine which are available in the market as single dose immediate release tablets. So the patients don’t have to take two tablets. It will also reduce the cost of the tablet as immediate- release tablet or extended- release tablet.

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