Volume 14 | Issue 3
Volume 14 | Issue 3
Volume 14 | Issue 2
Volume 14 | Issue 2
Volume 14 | Issue 2
The aim of the study is to explore the complex connection between excess weight and type 2 diabetes in the context of one of the leading causes of profound shifts in health in India. Both diseases are on the rise, with 23.5% of Indian adults being overweight or obese and the percentage of people with diabetes residing at 12.3%. The Indian population has unique aspects of their biology that are referred to as the “Asian Indian Phenotype”. Indians are more resistant to the effects of insulin and have greater stores of abdominal fat at most BMI levels compared to the Western population. This review amalgamates results from several epidemiological studies. It also examines the multilayered mechanisms of the connection of these two conditions, such as genetic, lifestyle, and socioeconomic factors. Various strategies to curb the impact of the causal connection of the two states are also discussed. The key pathways through which excess weight relates to type 2 diabetes in this area are evaluated as well as their relative contributions. Those include insulin resistance with its multiple repercussions, beta-cell dysfunction, irregular levels of adipokines, and the ectopic presence of adipose tissue