IJFANS International Journal of Food and Nutritional Sciences

ISSN PRINT 2319 1775 Online 2320-7876

Evaluation of Gastro Protective Activity of Ethanolic Leaf Extract ofCassia grandis Linn against Aspirin Induced Peptic ulcer on Swiss albino Wistar Rats

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B.Arul,R. Sivaraman,S. Swathika,E. Manivannan,R.Kothai


This study examines the gastro protective activity of ethanolic leaf extract ofCassia grandis Linn against aspirin induced peptic ulcers on swiss albino wistar rat. Oral aspirin treatment (300 mg/kg body weight) caused ulceration. Omeprazole (standard) was given to swiss albino wistar rats at a dose of 20 mg/kg body weight, and Cassia grandis Linn was given at doses of 200 and 400 mg/kg body weight once daily for 14 days prior to the development of ulcers. Gastric secretions parameters were assessed after the experiment

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