One of the most terrible diseases and a major medical problem in the world, cancer has an unacceptable death rate and is becoming increasingly prevalent every day. Despite the advancement of modern hygiene systems, medicinal plants still serve a significant therapeutic role. In the research area, an ethnobotanical survey was carried out to learn more about the use of herbs in traditional cancer treatment. According to the study, cancer is treated with 35 medicinal plants from 24 botanical families and 33 genera. Four species each from the Fabaceae and Solanaceae families, three from the Rutaceae, Apocynaceae, Asclepiadaceae, and Verbenaceae. The most common plant portion employed by the population under study as cancer preventative was leaves. The most popular technique for making remedies was the combination of Powder and decoction. According to public citations, the most significant plants for battling cancer include Vitex negundo, Tinospora cordifolia, Aloe vera, Achyranthes aspera, Withania somnifera, Azadirachta indica, Premna latifolia, Cynodon dactylon, Datura innoxia, and Dalbergia sissoo. More research should be explored to find practical phytochemical components and active ingredientsthat could be helpful for the treatment of cancer.