Nigella sativa, commonly known as black seed, has garnered significant attention due to its potential health benefits. This review assesses existing research focused on the comparative antidiabetic and antioxidant properties of Nigella sativa. It examines studies investigating the impact of Nigella sativa extracts and oil on controlling blood sugar levels and enhancing antioxidant enzyme activity in diabetic models. The review evaluates the effectiveness of different preparations of Nigella sativa and explores the potential mechanisms that underlie its therapeutic effects. By synthesizing findings from diverse studies, this review aims to offer a comprehensive overview of the current evidence regarding Nigella sativa's role in managing diabetes and its antioxidant properties.