Insecticides and Pesticides play vital roles in modern agricultural practices and effective domestic pest control. insecticides and Pesticides, generally including carbamate, organophsphorus, and organochlorine, etc, are also increasing the graph of mortality. The various Chromatographic methods, notably gas-liquid chromatography have been traditionally used to analyze the sample and their metabolites in different matrices these techniques help in identifying and quantifying the compounds. The objective of this research paper is to determine the efficient and accurate instrument for the analysis of the agricultural poison based on the retention time and concentration of the injected volume of the standard sample.